Epidural clonidine applied as an adjunct to area anesthetics has 3 unique mechanisms of action. Initial, the stimulation of alpha-2-receptors in the dorsal horn lessens pain transmission. Secondly, clonidine could potentially cause area vasoconstriction that limits vascular removal of area epidural anesthetics. May be offered as monotherapy or as https://georgesd491azx5.wikipublicity.com/user